What are we vaccinating against?
In the UK we currently recommend vaccinating rabbits against two diseases; Myxomatosis and Rabbit Viral Haemorrhagic Disease (RHD). Due to a new emerging strain of RHD we recommend vaccination twice a year and vaccination can start at 5-7 weeks of age.
We recommend these vaccinations are given 6 months apart, but they can be given 2 weeks apart. A full clinical examination will be conducted at the time of vaccination to check your rabbit is fit and healthy and is a great chance to ask our veterinary team any husbandry, nutrition or welfare questions.
What is Myxomatosis?
Myxomatosis is a disease caused by the myxoma virus and has been present in the UK since 1953. In unprotected rabbits, the disease is usually fatal and so prevention is strongly recommended.
What are the symptoms of Myxomatosis?
There are two types of myxomatosis, nodular (lumpy) and oedematous (swollen) but the latter is the most common and the most lethal. Symptoms begin between 4-10 days after infection:
Nodular (lumpy) Type
- Lumps in and/or under the skin
- Lumps become ulcerated (open wound) but can heal over
- Secondary infections
Oedematous (swollen) Type
- Swelling around the eyes, mouth, bottom and/or genitals
- Decreased appetite
- Dull behaviour
- Light sensitivity
- Secondary infections (eyes, nose, lungs)
- Weight loss
- Difficulty breathing (end stage) and death
It is possible for rabbits to get a mixed form with symptoms from both types of the disease which may be milder. The oedematous form acts quickly and after around 1-2 weeks of symptoms rabbits will die from starvation and difficulty breathing.
How do rabbits get Myxomatosis?
Rabbits can become infected with the virus from direct contact with other infected rabbits but also from being bitten by blood sucking-insects with the virus. These insects become carriers when they feed on infected rabbits and spreading it as they fed on other rabbits. Any blood-sucking insect can be a carrier but fleas and mosquitoes are the most common and because mosquitoes can fly long distances, they also help spread the disease to new areas.
Can you treat Myxomatosis?
Treatment of the oedematous form is usually hopeless, particularly if the rabbit is already having difficulty eating or breathing. Due to this our vets sadly will most likely recommend euthanasia to stop the rabbit from suffering. Rabbits with a mixed form of the disease may be able to survive with supportive care if the disease is mild. Supportive treatment is typically aimed at maintaining adequate nutrition and alleviating other symptoms while the immune system clears the virus.
What is Rabbit Haemorrhagic Disease (RHD)?
RHD is a deadly disease caused by a calicivirus which can be transmitted both directly and indirectly. The RHD virus is currently divided into subtypes including RHD1 and RHD2. The virus has been present in Europe since 1988 but an outbreak of RHD2 in the UK started in 2013 and has caused a large number of rabbit deaths.
In recent years , a new highly virulent strain of RHD have been reported in Europe, and in 2025, some isolated cases have been reported in the UK, and the disease is expected to become more widespread over time.
What are the symptoms of RHD?
Sadly, one of the most common symptoms of RHD is sudden death, with many owners believing their rabbit died of “fright” or a heart attack. External symptoms are not always seen and so many rabbits dying from RHD are not known, meaning the disease is likely more widespread than we think. The disease acts so quickly (within 1-3 days of infection) that rabbits can look completely normal the day before.
Possible symptoms can include:
- Sudden death
- Bleeding from the nose/mouth/bottom
- Lethargy
- Decreased appetite
- Difficulty breathing
- Fever (early)
- Seizures
- Vocalising
- Collapse
A mild form of the disease does exist but this is very uncommon and those rabbits are normally just generally unwell with non-specific symptoms which often mean we do not recognise they have RHD.
How do rabbits get RHD?
The virus can survive in the environment for many months, especially when it’s cold, allowing it to cause disease outbreaks year after year. RHD can infect rabbits directly through bodily fluids such as faeces/urine/saliva and mating as well as indirectly by contaminated objects such as clothing/cages/bedding/food/humans as well as insects, birds and rodents carrying the disease. There is even suspicion the virus can be carried on the wind. Blood-sucking insects such as mosquitoes and fleas can cause the virus to spread quickly and over considerable distances.
Can it be treated?
RHD is usually fatal and cannot be treated so vaccinating your rabbit is strongly recommended to prevent them from getting it. We may be able to provide some supportive care to infected rabbits but normally our vets will recommend euthanasia to alleviate suffering. Rabbits known, or suspected, of being infected should be isolated from all other rabbits and strict hygiene protocols used to prevent the virus from being transported elsewhere. All equipment and housing should be thoroughly disinfected and cleaned.
How can I prevent my rabbit from getting these viral diseases?
The Rabbit Welfare Association & Fund (RWAF) currently advises that the best protection against all variants of Rabbit Haemorrhagic Disease (RHD) is twice-yearly vaccination using two different vaccines.
- The first vaccine protects against Myxomatosis and RHD.
- The second vaccine protects against the newer, emerging strain of RHD.
Rabbits can begin vaccination from 5–7 weeks of age. We recommend giving the two vaccines six months apart, although they can be administered as close as two weeks apart if needed.
Each vaccination appointment includes a full clinical examination to ensure your rabbit is fit and healthy. It’s also the perfect opportunity to ask our veterinary team any questions about rabbit care and husbandry.
As well as vaccination, good husbandry can reduce the risk of viral diseases:
- Ensure your rabbit does not have contact with wild rabbits, birds or rodents which may be infected, or eat food from areas where wild rabbits live.
- Protect your rabbits from insects that may carry the disease by using insect screens and flea prevention spot-ons.
- If you’re introducing a new rabbit, quarantine it for at least a fortnight to ensure it is not infected before exposing it to your current rabbit/s.
- We advise that all objects (e.g. water bottles, bowls, cleaning equipment) are cleaned and disinfected regularly as well as your rabbit’s housing.
- Bedding should be changed regularly and along with hay, should be sourced from a supplier where it has been grown with no known infected wild rabbits.
- To reduce the risk of the new strain of RHD, avoid feeding feed imported from Europe
- Keep outdoor footwear away from rabbits – i.e. walking boots etc that could bring infection into your household and garden
As always, if you have any concerns or questions, please get in touch with our team. Routine appointments can be booked online, and if you’re not yet registered with us, you can complete your registration online too.